Is physical activity a risk factor for primary knee or hip replacement due to osteoarthritis? A prospective cohort study

Y Wang; JA Simpson; AE Wluka; AJ Teichtahl; DR English; GG Giles; S Graves; FM Cicuttini

Journal article

Is physical activity a risk factor for primary knee or hip replacement due to osteoarthritis? A prospective cohort study

Y Wang, JA Simpson, AE Wluka, AJ Teichtahl, DR English, GG Giles, S Graves, FM Cicuttini

Journal of Rheumatology | Published : 2011

DOI: 10.3899/jrheum.091138

Abstract

Objective. To estimate prospectively any association between measures of physical activity and the risk of either primary knee or hip replacement due to osteoarthritis (OA). Methods. Eligible subjects (n = 39,023) were selected from participants in a prospective cohort study recruited 1990-1994. Primary knee and hip replacement for OA during 2001-2005 was determined by linking the cohort records to the National Joint Replacement Registry. A total physical activity level was computed, incorporating both intensity and frequency for different forms of physical activity obtained by questionnaire at baseline attendance. Results. There was a dose-response relationship between total physical activi..

View full abstract

University of Melbourne Researchers

Julie Simpson Author

Dallas English Author

Graham Giles Author

Related Projects (3)

PLATYPUS

This proposal builds on the applicants’ experience with existing large prospective studies and on studies of families of patients with bowel..

Epidemiology of chronic disease, health interventions and DNA studies

THE HEALTH 2020 COHORT STUDY (HEALTH 2020)

Our aim is to develop appropriate infrastructures necessary to facilitate access by researchers to the accumulated data, including questionn..

Grants

Awarded by National Health and Medical Research Council (NHMRC)

Awarded by NHMRC Public Health (Australia)

Funding Acknowledgements

The Melbourne Collaborative Cohort Study recruitment was funded by VicHealth and The Cancer Council of Victoria. This study was supported by a program grant from the National Health and Medical Research Council (NHMRC; 209057), capacity building grant (251533), and enabling grant (396414), and was further supported by infrastructure provided by The Cancer Council of Victoria. Dr. Wang and Dr. Wluka received NHMRC Public Health (Australia) Fellowships (NHMRC 465142 and 317840, respectively).